Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6100085 | 0.80 | HSD11B1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6484387 | 0.79 | MAPT (0.34) | — | |
| Hydrochloric Acid SCHEMBL6100055 | 0.77 | CRHR1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1974315 | 0.76 | KDM4E (0.31) | — | |
| Hydrochloric Acid SCHEMBL547963 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6483898 | 0.75 | POLB (0.32) | — | |
| Hydrochloric Acid SCHEMBL919094 | 0.75 | HPGD (0.35) | — | |
| Hydrochloric Acid SCHEMBL919442 | 0.74 | — | — | |
| Bromide SCHEMBL3667202 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL920628 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084222-B2 | Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst | ZEON CORPORATION (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20050014916-A1 | Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst | ZEON CORPORATION (JP) | 2005-01-20 | — | — | US | disclosed |