Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680561 | 0.89 | FKBP1A (0.66) | FKBP1A | |
| SCHEMBL6100689 | 0.80 | FKBP1A (0.72) | FKBP1A | |
| SCHEMBL6099159 | 0.79 | FKBP1A (0.71) | FKBP1A | |
| SCHEMBL4677088 | 0.79 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL7757995 | 0.79 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL5834087 | 0.79 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL6101759 | 0.77 | FKBP1A (0.59) | FKBP1A | |
| SCHEMBL4677091 | 0.77 | FKBP1A (0.82) | FKBP1A | |
| SCHEMBL7424656 | 0.77 | FKBP1A (0.80) | FKBP1A | |
| SCHEMBL7761797 | 0.77 | FKBP1A (1.00) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984639-B2 | Heterocyclic ketone and thioester compounds and uses | GPI NIL HOLDINGS, INC. (US) | 2006-01-10 | — | — | US | disclosed |
| US-20040106652-A1 | Heterocyclic ketone and thioester compounds and uses | GPI NIL HOLDINGS, INC. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106652-A1 | Heterocyclic ketone and thioester compounds and uses | BDNF, NTRK2, NTRK1 | FKBP1A 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.