Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 3/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101108 | 0.77 | MAPT (0.39) | HPGDALDH1A1 | |
| SCHEMBL6101116 | 0.77 | MAPT (0.39) | HPGDALDH1A1 | |
| SCHEMBL4158476 | 0.76 | KDM4E (0.46) | HPGDSMN1; SMN2ADORA2BRXFP1PDE4A | |
| SCHEMBL6099895 | 0.74 | MEN1 (0.45) | SMN1; SMN2ADORA2BRXFP1PDE4APARN | |
| SCHEMBL6098712 | 0.73 | HSP90AB1 (0.39) | HPGDSMN1; SMN2PDE4AALDH1A1 | |
| SCHEMBL6101023 | 0.71 | ALDH1A1 (0.42) | HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4145710 | 0.70 | ALDH1A1 (0.39) | HPGDSMN1; SMN2PARNCNOT7ALDH1A1 | |
| SCHEMBL6101896 | 0.70 | TSHR (0.52) | HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6101048 | 0.68 | USP2 (0.39) | HPGDALDH1A1 | |
| SCHEMBL1947260 | 0.68 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2ADORA2BRXFP1PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | VERSCHUEREN GASTON W | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | SULT1A1, SULT2A1, SULT1E1 | HPGD 347/4885SMN1; SMN2 3615/4885ADORA2B 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.