Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6104382 | 1.00 | ALDH1A3 (0.49) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL6103643 | 1.00 | ALDH1A3 (0.49) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL6104298 | 0.98 | ALDH1A1 (0.49) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL4471820 | 0.86 | ALDH1A1 (0.47) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL3688200 | 0.85 | ALDH1A1 (0.41) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL4528462 | 0.84 | ALDH1A1 (0.49) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL3686814 | 0.83 | HTT (0.44) | ALDH1A1SMN1; SMN2ERN1MAPTMEN1 | |
| SCHEMBL6102716 | 0.83 | ALDH1A1 (0.61) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL29914855 | 0.83 | ALDH1A1 (0.61) | ALDH1A3ALDH1A1SMN1; SMN2ERN1MAPT | |
| SCHEMBL29964936 | 0.83 | ERN1 (0.43) | ALDH1A3ALDH1A1SMN1; SMN2ERN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160864-A1 | Acrylamide derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1593673-A1 | ACRYLAMIDE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160864-A1 | Acrylamide derivative, process for producing the same, and use | CCR5, MSR1, CCR2 | ALDH1A3 3397/4885ALDH1A1 1414/4885SMN1; SMN2 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.