Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715020 | 0.92 | KDM4E (0.45) | KDM4EALDH1A1MGLLCYP1A2CYP3A4 | |
| SCHEMBL6101933 | 0.90 | ALDH1A1 (0.56) | KDM4EALDH1A1 | |
| SCHEMBL6102707 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1APPMGLLCYP1A2 | |
| SCHEMBL5714775 | 0.85 | KMT2A (0.44) | KDM4EALDH1A1APP | |
| SCHEMBL6102650 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1 | |
| SCHEMBL5714942 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1APPMGLL | |
| SCHEMBL5714785 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1THRB | |
| SCHEMBL6099837 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1MGLLCYP1A2CYP3A4 | |
| SCHEMBL6102884 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1MGLLCYP1A2CYP3A4 | |
| SCHEMBL5715470 | 0.83 | AOC3 (0.42) | KDM4EALDH1A1MGLLCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160820-A1 | Substituted piperazine carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | claimed |
| US-20060160820-A1 | Substituted piperazine carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160820-A1 | Substituted piperazine carbamates | LIPE, PNLIP, LPL | KDM4E 1090/4885ALDH1A1 1504/4885APP 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.