Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968730 | 0.91 | HTT (0.43) | HTTADRA1DADRA1AADRA1BSLC6A4 | |
| SCHEMBL14364263 | 0.91 | HTT (0.43) | HTTADRA1DADRA1AADRA1BSLC6A4 | |
| SCHEMBL4964306 | 0.87 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BSLC6A4HTR1A | |
| SCHEMBL4960749 | 0.85 | CA2 (0.42) | ADRA1DADRA1AADRA1BSLC6A4CA2 | |
| SCHEMBL4984814 | 0.85 | ADRA1D (0.48) | HTTADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6103982 | 0.83 | AQP1 (0.44) | HTTADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4961223 | 0.82 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL8131145 | 0.80 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BSLC6A4HTR1A | |
| SCHEMBL6107379 | 0.80 | HTT (0.40) | HTTADRA1DADRA1AADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL8126727 | 0.79 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BSLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | HTR2C, HTR1D, HTR1A | HTT 2102/4885ADRA1D 21/4885ADRA1A 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.