Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108314 | 0.90 | PGR (0.39) | MAPK8DPP4 | |
| SCHEMBL6109676 | 0.88 | DPP4 (0.35) | DPP4 | |
| SCHEMBL6107482 | 0.87 | NR1H3 (0.34) | MAPK8DPP4 | |
| SCHEMBL6107104 | 0.86 | RORA (0.36) | DPP4 | |
| SCHEMBL6108888 | 0.86 | RORA (0.36) | MAPK8DPP4 | |
| SCHEMBL6110129 | 0.86 | DPP4 (0.42) | MAPK8DPP4 | |
| SCHEMBL6108268 | 0.85 | DPP4 (0.35) | DPP4 | |
| SCHEMBL6106644 | 0.85 | LMNA (0.38) | MAPK8DPP4 | |
| SCHEMBL6109932 | 0.85 | KDM4E (0.34) | DPP4 | |
| SCHEMBL6107387 | 0.85 | HTT (0.35) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |