⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140084 | 0.80 | — | — | |
| SCHEMBL27815234 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL10606 | 0.79 | HDAC6 (0.37) | — | |
| SCHEMBL25946603 | 0.77 | PPARA (0.33) | — | |
| SCHEMBL6154635 | 0.77 | CYP2D6 (0.45) | — | |
| SCHEMBL241533 | 0.77 | DGAT1 (0.46) | — | |
| SCHEMBL644646 | 0.77 | TSHR (0.45) | — | |
| SCHEMBL2963000 | 0.76 | HDAC6 (0.42) | — | |
| SCHEMBL418887 | 0.75 | EPHX2 (0.39) | — | |
| SCHEMBL63935 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812474-A | Water-soluble coumarin-based light-controlled latent incense body and preparation method and application thereof | 上海应用技术大学 | 2024-10-22 | — | — | CN | claimed |
| WO-2022219485-A1 | A SCALABLE PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE GLYCINE TERT-BUTYL ESTER AND ITS SALT THEREOF | HIKAL LIMITED (IN) | 2022-10-20 | — | — | WO | claimed |
| CN-113880850-B | Gadobutrol intermediate, preparation method and application in gadobutrol preparation | 苏州百灵威超精细材料有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-113880850-A | Gadobutrol intermediate, preparation method and application in gadobutrol preparation | 苏州百灵威超精细材料有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-113461591-A | Preparation method of precursor raw material Pht-AEEA-AEEA for side chain of Somalutide | 浙江泽瑞生物医药有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-112961113-A | Preparation method of ambroxol hydrochloride impurity | 北京新康哌森医药科技有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-110078644-B | preparation method of [2- [1- (Fmoc-amino) ethoxy ] acetic acid | 深圳市茵诺圣生物科技有限公司 | 2019-12-17 | — | — | CN | claimed |
| CN-103965047-B | The preparation method of 3,3,3-trifluoroacetic acid and ester thereof | XI'AN INST. OF MODERN CHEMISTRY (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-104418707-A | Natural product fructus psoraleae phenol and asymmetric synthesis method of enantiomer thereof | UNIV FUDAN | 2015-03-18 | — | — | CN | claimed |
| CN-103965047-A | Method for preparing 3,3,3-trifluoropropionic acid and ester thereof | XIAN MODERN CHEMISTRY RES INST | 2014-08-06 | — | — | CN | claimed |
| CN-101628894-B | Preparation method of 3-(S)-amino-2, 3,4, 5-tetrahydro-2-oxo-1H-1-benzoaza-1-tert-butyl acetate | ZHEJIANG SANHE PHARMACEUTICAL CHEMICAL CO LTD | 2011-06-29 | — | — | CN | claimed |
| CN-101628894-A | Preparation method of 3- (S) -amino-2, 3,4, 5-tetrahydro-2-oxo-1H-1-benzazepine-1-tert-butyl acetate | ZHEJIANG SANHE PHARMACEUTICAL | 2010-01-20 | — | — | CN | claimed |
| WO-2009056077-A2 | A NEW METHOD OF MANUFACTURING 2-(6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-LH-PYRROLIZINE-5-YL)ACETIC ACID (LICOFELONE) | ZENTIVA, A.S. (CZ) | 2009-05-07 | — | — | WO | claimed |
| US-20250353864-A1 | INDAZOLE CONTAINING MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4536224-A1 | INDAZOLE CONTAINING MACROCYCLES AND THEIR USE | Blossomhill Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119421709-A | Indazole-containing macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-0049505-A2 | Substituted caprolactam derivatives, a process for preparing and a pharmaceutical composition containing the same, and intermediates | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| EP-0046289-A2 | Substituted enantholactam derivatives as antihypertensives, a process for preparing and a pharmaceutical composition containing them, and intermediates | MERCK & CO. INC. (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0046292-A1 | Substituted caprylolactam derivatives as antihypertensives, process for preparing and pharmaceutical composition comprising them | MERCK & CO. INC. (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0046291-A2 | Substituted caprolactam derivatives as antihypertensives, process for preparing them, pharmaceutical composition containing them, and intermediates | MERCK & CO. INC. (US) | 1982-02-24 | — | — | EP | disclosed |