Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dnqx SCHEMBL1258964 | 0.86 | POLB (0.57) | PGK1ALDH1A1LMNAGPR35GALR2 | |
| SCHEMBL1291907 | 0.85 | PGK1 (0.61) | PGK1ALDH1A1CYP3A4LMNAGALR2 | |
| SCHEMBL6108459 | 0.78 | POLB (0.44) | ALDH1A1CYP3A4LMNAGPR35GALR2 | |
| SCHEMBL6109752 | 0.78 | POLB (0.44) | ALDH1A1CYP3A4LMNAGPR35GALR2 | |
| SCHEMBL7825439 | 0.77 | PGK1 (0.53) | PGK1ALDH1A1CYP3A4LMNAPOLB | |
| SCHEMBL14973435 | 0.76 | PTPN11 (0.57) | PGK1ALDH1A1CYP3A4LMNAGPR35 | |
| SCHEMBL8551999 | 0.75 | PGK1 (0.45) | PGK1ALDH1A1CYP3A4LMNAGALR2 | |
| SCHEMBL16082531 | 0.75 | EGFR (0.51) | PGK1ALDH1A1CYP3A4LMNAGPR35 | |
| SCHEMBL21591903 | 0.75 | PGK1 (0.55) | PGK1ALDH1A1CYP3A4LMNAGALR2 | |
| SCHEMBL21591867 | 0.75 | PGK1 (0.55) | PGK1ALDH1A1CYP3A4LMNAGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081346-B2 | Method of screening binding of a compound to a receptor | MARQUETTE UNIVERSITY (US) | 2006-07-25 | — | — | US | disclosed |
| US-20030215959-A1 | Method of screening binding of a compound to a receptor | MARQUETTE UNIVERSITY | 2003-11-20 | — | — | US | disclosed |
| EP-0260467-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1993-12-29 | — | — | EP | disclosed |
| US-4812458-A | 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics | A/S FERROSAN (DK) | 1989-03-14 | — | — | US | disclosed |
| EP-0260467-A2 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215959-A1 | Method of screening binding of a compound to a receptor | FSHR, GRB7, GPR174 | PGK1 2350/4885ALDH1A1 3903/4885CYP3A4 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.