Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dnqx SCHEMBL1258964 | 0.86 | POLB (0.57) | POLBLMNAGPR35GALR2TDP1 | |
| SCHEMBL6108459 | 0.78 | POLB (0.44) | POLBLMNAGPR35GALR2TDP1 | |
| SCHEMBL6109031 | 0.78 | PGK1 (0.58) | POLBLMNAGPR35GALR2MAPT | |
| SCHEMBL6111459 | 0.76 | CA2 (0.47) | POLBLMNAGPR35GALR2TDP1 | |
| SCHEMBL10348834 | 0.75 | MAPT (0.52) | POLBLMNATDP1MAPTMEN1 | |
| SCHEMBL19511923 | 0.75 | MAPT (0.62) | POLBLMNAGPR35TDP1MAPT | |
| SCHEMBL596168 | 0.75 | MAPT (0.62) | POLBLMNAGPR35TDP1MAPT | |
| SCHEMBL31237002 | 0.74 | POLB (0.57) | POLBLMNAGALR2TDP1MAPT | |
| SCHEMBL28979816 | 0.74 | POLB (0.57) | POLBLMNAGALR2TDP1MAPT | |
| SCHEMBL11809474 | 0.74 | L3MBTL1 (0.59) | POLBLMNAGPR35TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081346-B2 | Method of screening binding of a compound to a receptor | MARQUETTE UNIVERSITY (US) | 2006-07-25 | — | — | US | disclosed |
| US-20030215959-A1 | Method of screening binding of a compound to a receptor | MARQUETTE UNIVERSITY | 2003-11-20 | — | — | US | disclosed |
| EP-0260467-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1993-12-29 | — | — | EP | disclosed |
| US-4812458-A | 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics | A/S FERROSAN (DK) | 1989-03-14 | — | — | US | disclosed |
| EP-0260467-A2 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-03-23 | — | — | EP | disclosed |
| EP-0010722-B1 | MONOAZO-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-20 | — | — | EP | disclosed |
| US-4312807-A | HEAT RESISTANT PIGMENTS FOR POLYVINYL CHLORIDE AND POLYETHYLENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0010722-A1 | Monoazo-compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215959-A1 | Method of screening binding of a compound to a receptor | FSHR, GRB7, GPR174 | POLB 4185/4885LMNA 4600/4885GPR35 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.