Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205655 | 0.86 | SMN1; SMN2 (0.53) | P2RX4ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL29549990 | 0.86 | SMN1; SMN2 (0.53) | P2RX4ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7161164 | 0.86 | P2RX4 (0.48) | P2RX4ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL6110992 | 0.82 | SMN1; SMN2 (0.44) | P2RX4ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8768858 | 0.82 | P2RX4 (0.43) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL6110761 | 0.82 | P2RX4 (0.46) | P2RX4ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8769449 | 0.80 | P2RX4 (0.43) | P2RX4SMN1; SMN2LMNAP2RX1P2RX3 | |
| SCHEMBL3719677 | 0.80 | BCHE (0.50) | P2RX4ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL27785934 | 0.80 | P2RX4 (0.58) | P2RX4TSHRSMN1; SMN2LMNASCN9A | |
| SCHEMBL28802473 | 0.80 | P2RX4 (0.63) | P2RX4ALDH1A1SMN1; SMN2P2RX1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006033004-A1 | QUINOLINE COMPOUNDS AS CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| EP-0819135-A1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031532-A1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-10 | — | — | WO | disclosed |