Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110992 | 0.92 | SMN1; SMN2 (0.44) | BCHETSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL205655 | 0.88 | SMN1; SMN2 (0.53) | BCHETSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL29549990 | 0.88 | SMN1; SMN2 (0.53) | BCHETSHRL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL27460751 | 0.86 | BCHE (0.52) | BCHETSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL411007 | 0.86 | SMN1; SMN2 (0.44) | BCHETSHRSMN1; SMN2LMNAP2RX4 | |
| SCHEMBL29639604 | 0.86 | SMN1; SMN2 (0.44) | BCHETSHRSMN1; SMN2LMNAP2RX4 | |
| SCHEMBL6110401 | 0.80 | P2RX4 (0.64) | TSHRSMN1; SMN2LMNAP2RX4MEN1 | |
| SCHEMBL27785934 | 0.79 | P2RX4 (0.58) | BCHETSHRSMN1; SMN2LMNAP2RX4 | |
| SCHEMBL28802473 | 0.78 | P2RX4 (0.63) | TDP1L3MBTL1SMN1; SMN2P2RX4MEN1 | |
| SCHEMBL8769449 | 0.76 | P2RX4 (0.43) | BCHEL3MBTL1SMN1; SMN2LMNAP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097091-A1 | METHODS OF ADMINISTERING (4AR, 1OAR)-I-N-PROPYL-I, 2,3,4A7 S1IO7 IOA-OCTAHYDROBENZO [G] QUINOLINE-6,7-DIOL AND RELATED COMPOUNDS ACROSS THE ORAL MUCOSA, THE NASAL MUCOSA OR THE SKIN AND PHARMACEUTICAL COMPOSITIONS THEREOF | H. LUNDBECK A/S (DK) | 2010-09-02 | — | — | WO | disclosed |