Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 10/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110761 | 0.86 | P2RX4 (0.46) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL22264116 | 0.85 | P2RX4 (0.41) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL205655 | 0.82 | SMN1; SMN2 (0.53) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL29549990 | 0.82 | SMN1; SMN2 (0.53) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL8768858 | 0.81 | P2RX4 (0.43) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL6110401 | 0.80 | P2RX4 (0.64) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL27785934 | 0.79 | P2RX4 (0.58) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL6110992 | 0.78 | SMN1; SMN2 (0.44) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL3719677 | 0.76 | BCHE (0.50) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 | |
| SCHEMBL411007 | 0.75 | SMN1; SMN2 (0.44) | P2RX4P2RX1P2RX3SMN1; SMN2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793967-A2 | Conjugated compounds of bile acids with thiotaurine and its N-alkyl derivatives | PRODOTTI CHIMICI E ALIMENTARI SPA (IT) | 1997-09-10 | — | — | EP | disclosed |