Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112256 | 0.90 | KCNA5 (0.41) | HRH3KCNA5KCNE1ALDH1A1KDM4E | |
| SCHEMBL6110516 | 0.73 | LOXL2 (0.45) | HRH3KCNA5KCNE1ALDH1A1KDM4E | |
| SCHEMBL7187375 | 0.73 | L3MBTL1 (0.51) | HRH3CYP2D6ALDH1A1MEN1KMT2A | |
| SCHEMBL11904339 | 0.72 | LOXL2 (0.46) | CYP2D6ALDH1A1MAPTCYP2C19 | |
| SCHEMBL263407 | 0.72 | LOXL2 (0.50) | CYP2D6ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL8074159 | 0.69 | CYP1A2 (0.66) | HRH3KCNA5KCNE1CYP2D6ALDH1A1 | |
| SCHEMBL13039159 | 0.69 | CYP1A2 (0.66) | HRH3KCNA5KCNE1CYP2D6ALDH1A1 | |
| SCHEMBL8074161 | 0.69 | CYP1A2 (0.66) | HRH3KCNA5KCNE1CYP2D6ALDH1A1 | |
| SCHEMBL5592048 | 0.69 | HRH3 (0.43) | HRH3CYP2D6ALDH1A1KDM4EMEN1 | |
| SCHEMBL8002386 | 0.68 | MC4R (0.49) | CYP2D6ALDH1A1OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099884-A1 | BETA-AMINOALCOHOL ANTIBIOTICS | ACTELION PERCUREX AG (CH) | 2006-09-28 | — | — | WO | disclosed |