SCHEMBL6112

SCHEMBL6112

CN(C)C(=O)N1CCNCC1

nearest known ligand 0.84

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
CA2 P00918 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA9 Q16790 1/20 0.48
CHKA P35790 1/20 0.46
CHRNB2 P17787 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
CHRNB3 Q05901 1/20 0.45
CHRNA6 Q15825 1/20 0.45
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SIGMAR1 Q99720 1/20 0.39
GAA P10253 1/20 0.39
HSD11B1 P28845 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3845854 0.98 MAPT (0.47) MAPTCA2CA12CA1CA9
Hydrochloric Acid SCHEMBL27626557 0.98 MAPT (0.47) MAPTCA2CA12CA1CA9
SCHEMBL2919264 0.92 CA2 (0.50) MAPTCA2CA12CA1CA9
Trifluoroacetic Acid SCHEMBL2044334 0.87 PKM (0.46) MAPTCA2CA12CA1CA9
SCHEMBL28465070 0.86 MAPT (0.41) MAPTCA2CA12CA1CA9
SCHEMBL25703358 0.82 CA2 (0.45) MAPTCA2CA12CA1CA9
SCHEMBL282864 0.82
Trifluoroacetic Acid SCHEMBL29701080 0.81 PKM (0.42) MAPTCA2CA12CA1CA9
Tert-Butyl Formate SCHEMBL28060441 0.81 TDP1 (0.41) MAPTCA2CA12CA1CA9
SCHEMBL8530598 0.80 CA2 (0.43) CA2CA12CA1CA9CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025046148-A1 NOVEL PARG INHIBITORS FORX THERAPEUTICS AG (CH) 2025-03-06 WO claimed
EP-3652180-B1 SUBSTITUTED BENZOXAZOLE AND BENZOFURAN COMPOUNDS AS PDE7 INHIBITORS DART NEUROSCIENCE LLC (US) 2023-11-29 EP claimed
CN-115806550-A Bicyclic BET bromodomain inhibitors and uses thereof 康威基内有限公司 2023-03-17 CN claimed
CN-110036006-B Preparation and use of pyrimidinone derivatives 癌症研究科技有限公司 2022-12-13 CN claimed
EP-3433249-B1 BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST COUNCIL SCIENT IND RES (IN) 2022-11-09 EP claimed
US-20220306610-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS ARDELYX, INC. (US) 2022-09-29 US claimed
CN-109651297-B N-benzyl-N-aryl sulfonamide derivative and preparation and application thereof 杭州壹瑞医药科技有限公司 2022-05-27 CN claimed
CN-113226469-A Imidazopyrazine derivatives as antibacterial agents 豪夫迈·罗氏有限公司 2021-08-06 CN claimed
CN-102625799-A Heterocyclic compounds and their uses AMGEN INC 2012-08-01 CN claimed
CN-102548984-A Inhibitors of PI3 kinase and / or MTOR AMGEN INC 2012-07-04 CN claimed
EP-1945624-A1 CHROMAN COMPOUNDS AS 5-HT1B ANTAGONISTS Astra Zeneca AB (SE) 2008-07-23 EP claimed
WO-2007053095-A1 CHROMAN COMPOUNDS AS 5-HT1B ANTAGONISTS ASTRAZENECA AB (SE) 2007-05-10 WO claimed
CN-1390215-A Tyrosine kinase inhibitors MERCK & CO INC (US) 2003-01-08 CN claimed
US-4348389-A Quinoxaline adducts useful as anthelmintics INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-09-07 US claimed
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES INC (US) 2026-05-14 US disclosed
US-12612427-B2 Aryl glucoside derivative, preparation method therefor and application thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2026-04-28 US disclosed
US-20260069605-A1 KRAS INHIBITORS INCYTE CORP (US) 2026-03-12 US disclosed
US-4348389-A Quinoxaline adducts useful as anthelmintics INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-09-07 US disclosed
US-4147785-A Method for the treatment of onchocerciasis Dobbie, Graham J. (US) 1979-04-03 US disclosed
US-4093726-A HYPOTENSIVE AGENTS ABBOTT LABORATORIES (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics NCOR1, HAVCR2, NR3C1 MAPT 3761/4885CA2 1795/4885CA12 975/4885
US-20220306610-A1 COMPOUNDS USEFUL FOR TREATING GASTROINTESTINAL TRACT DISORDERS SLC10A2, FABP2, SLC10A1 MAPT 4094/4885CA2 1499/4885CA12 3331/4885
US-12612427-B2 Aryl glucoside derivative, preparation method therefor and application thereof SLC5A1, SLC10A1, SLC5A2 MAPT 3930/4885CA2 2718/4885CA12 2001/4885
US-20260069605-A1 KRAS INHIBITORS KRAS, NRAS, HRAS MAPT 4823/4885CA2 2797/4885CA12 3642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.