Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 15/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794763 | 0.86 | PTGDR2 (0.53) | KMT2AALDH1A1LMNAHPGDPTGDR2 | |
| SCHEMBL5793255 | 0.83 | DAO (0.42) | PLA2G7CYP3A4CYP2D6LMNAALOX15 | |
| SCHEMBL3540781 | 0.79 | PLA2G7 (0.59) | PLA2G7CYP3A4CYP2D6 | |
| SCHEMBL5792610 | 0.78 | PTGDR2 (0.36) | PLA2G7CYP3A4CYP2D6LMNAALOX15 | |
| SCHEMBL3537601 | 0.76 | PLA2G7 (0.59) | PLA2G7CYP3A4CYP2D6 | |
| SCHEMBL5793463 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3534760 | 0.76 | PLA2G7 (0.58) | PLA2G7CYP3A4CYP2D6 | |
| SCHEMBL3612929 | 0.75 | PLA2G7 (0.58) | PLA2G7CYP3A4CYP2D6 | |
| SCHEMBL3539710 | 0.75 | PLA2G7 (0.55) | MEN1KMT2APLA2G7CYP3A4CYP2D6 | |
| SCHEMBL6112570 | 0.75 | PLA2G7 (0.65) | PLA2G7CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063791-A1 | 3-BENZYLTHIO-1,2,4-TRIAZINE-5 (2H)-ONE AS PAF-AH INHIBITORS | BAYER HEALTHCARE AG (DE) | 2006-06-22 | — | — | WO | disclosed |