Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135618 | 0.82 | CA1 (0.36) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL28423598 | 0.80 | CA1 (0.40) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL6113132 | 0.80 | CA1 (0.32) | CA1CA2CA9 | |
| SCHEMBL11350925 | 0.77 | TSHR (0.43) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL17319467 | 0.75 | TSHR (0.42) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL2233250 | 0.75 | TSHR (0.42) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL6729264 | 0.75 | TSHR (0.42) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL28160424 | 0.74 | CA1 (0.48) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL23805180 | 0.73 | TSHR (0.40) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL225628 | 0.73 | CA2 (0.40) | TSHRCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833723-B | The manufacture method of cyclic sulfonic acid ester and intermediate thereof | 和光纯药工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| EP-2757102-B1 | Intermediate for producing a cyclic sulfonic acid ester | WAKO PURE CHEM IND LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-8969591-B2 | Method for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| EP-2463281-B1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEM IND LTD (JP) | 2014-10-22 | — | — | EP | disclosed |
| EP-2757102-A1 | 1,3-propanesultone derivative useful in the preparation of a 1,3-propenesultone derivative | Wako Pure Chemical Industries, Ltd. (JP) | 2014-07-23 | — | — | EP | disclosed |
| CN-103833723-A | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEM IND LTD | 2014-06-04 | — | — | CN | disclosed |
| US-20140142324-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-05-22 | — | — | US | disclosed |
| US-8673963-B2 | Method for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| CN-102471305-B | Process for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEM IND LTD | 2014-01-29 | — | — | CN | disclosed |
| EP-2463281-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | Wako Pure Chemical Industries, Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20120130089-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| CN-102471305-A | Process for producing cyclic sulfonic acid ester and intermediate thereof | WAKO PURE CHEM IND LTD | 2012-05-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142324-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | STS, TST, SULT1A1 | TSHR 1305/4885CA1 178/4885CA2 747/4885 |
| US-20120130089-A1 | METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF | STS, TST, SULT1A1 | TSHR 1305/4885CA1 178/4885CA2 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.