SCHEMBL6113534

SCHEMBL6113534

OCC1COC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 12/20 0.55
ADRA1A P35348 14/20 0.54
ADRA1B P35368 11/20 0.54
ADRA1D P25100 10/20 0.54
GAA P10253 1/20 0.54
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL748670 0.85 HTR1A (0.43) HTR1AADRA1AADRA1BADRA1DGAA
SCHEMBL11448804 0.82 ADRA1A (0.54) HTR1AADRA1AADRA1BADRA1DGAA
SCHEMBL20740660 0.82 CHRNA1 (0.44) HTR1AADRA1AADRA1BADRA1DGAA
SCHEMBL18978964 0.79 ADRA1A (0.48) HTR1AADRA1AADRA1BADRA1DGAA
SCHEMBL9314380 0.79 CHRM2 (0.42) HTR1AADRA1AADRA1BADRA1D
SCHEMBL28351399 0.78 CHRM2 (0.64) HTR1AADRA1AADRA1BADRA1DGAA
SCHEMBL6052978 0.76 ADRA1A (0.40) HTR1AADRA1AADRA1BADRA1D
SCHEMBL28812850 0.76 CHRM2 (0.39) HTR1AADRA1AADRA1BADRA1D
SCHEMBL28351294 0.76 ADRA1A (0.57) HTR1AADRA1AADRA1BADRA1DGAA
SCHEMBL749991 0.75 ADRA1A (0.43) HTR1AADRA1AADRA1BADRA1DGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103314088-B Comprise the 1,3-dioxolanes-4-carbinol compound lubricant oil composite as anti-wear additive 雪佛龙奥伦耐有限责任公司 2016-06-22 CN disclosed
EP-2643439-B1 LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES CHEVRON ORONITE CO (US) 2014-12-17 EP disclosed
EP-2643439-A2 LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES Chevron Oronite Company LLC (US) 2013-10-02 EP disclosed
US-8349777-B2 Lubricating composition containing 1,3-dioxolane-4-methanol compounds as antiwear additives CHEVRON ORONITE COMPANY LLC (US) 2013-01-08 US disclosed
WO-2012071154-A2 LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES CHEVRON ORONITE COMPANY LLC (US) 2012-05-31 WO disclosed
US-20120129744-A1 LUBRICATING COMPOSITION CONTAINING 1,3-DIOXOLANE-4-METHANOL COMPOUNDS AS ANTIWEAR ADDITIVES CHEVRON ORONITE COMPANY LLC 2012-05-24 US disclosed
US-5312950-A Method for purification of alcohols EASTMAN KODAK COMPANY (US) 1994-05-17 US disclosed