Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 17/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 13/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 13/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052735 | 0.77 | MGLL (0.38) | ADRA1AADRA1BHTR1AADRA1D | |
| SCHEMBL9314380 | 0.76 | CHRM2 (0.42) | ADRA1AADRA1BPTGS2HTR1AADRA1D | |
| SCHEMBL6113534 | 0.76 | HTR1A (0.55) | ADRA1AADRA1BHTR1AADRA1D | |
| SCHEMBL28812850 | 0.73 | CHRM2 (0.39) | ADRA1AADRA1BPTGS2HTR1AADRA1D | |
| SCHEMBL6547330 | 0.69 | CYP1A2 (0.37) | ADRA1AADRA1BHTR1AADRA1DCHRM2 | |
| SCHEMBL15218248 | 0.69 | MEN1 (0.40) | HTR1A | |
| SCHEMBL11375665 | 0.68 | DPP4 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28129655 | 0.68 | MMP2 (0.41) | — | |
| SCHEMBL18555665 | 0.68 | SIGMAR1 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| Benzyl Alcohol SCHEMBL16651422 | 0.68 | SIGMAR1 (0.52) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123949-B1 | Thermoplastic olefin copolymers and blends thereof | GEN ELECTRIC (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-0661333-B1 | Thermoplastic olefin copolymers and blends thereof | GEN ELECTRIC (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1123949-A2 | Thermoplastic olefin copolymers and blends thereof | GENERAL ELECTRIC COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0564243-B1 | Polyphenylene ether-graft-orthoester copolymer blends | GEN ELECTRIC (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0659834-B1 | Polycarbonate compositions comprising thermoplastic olefin copolymers | GEN ELECTRIC (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0564244-B1 | The functionalization of polyphenylene ethers with graftable orthoesters | GEN ELECTRIC (US) | 1998-06-24 | — | — | EP | disclosed |
| EP-0499717-B1 | Ethylenically unsaturated cyclic ortho esters | GEN ELECTRIC (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5691411-A | ORTHOESTER OR ORTHOCARBONATE-FUNCTIONALIZED OLEFIN POLYMERS, CARBOXYLATED OR OXIDIZED POLYPHENYLENE ETHER, POLYAMIDE | GENERAL ELECTRIC COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| EP-0519642-B1 | Polyphenylene ether-polyester blends compatibilized with ortho ester copolymers | GEN ELECTRIC (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0496116-B1 | Polymers of ethylenically unsaturated cyclic ortho esters | GEN ELECTRIC (US) | 1996-10-02 | — | — | EP | disclosed |
| EP-0564243-A1 | Polyphenylene ether-graft-orthoester copolymer blends | GENERAL ELECTRIC COMPANY (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5247006-A | Blends with polyesters, polyamides or polyolefins | GENERAL ELECTRIC COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5231132-A | Impact strength | GENERAL ELECTRIC COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| US-5212255-A | Functionalization of polyphenylene ether with graftable orthoester | GENERAL ELECTRIC COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0519642-A2 | Polyphenylene ether-polyester blends compatibilized with ortho ester copolymers | GENERAL ELECTRIC COMPANY (US) | 1992-12-23 | — | — | EP | disclosed |
| US-5171866-A | To compatibilize blends; forming epdm graft polymers | GENERAL ELECTRIC COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| US-5153290-A | Addition homo- or copolymer for blending with polyesters or polyamides; impact, tensile strength | GENERAL ELECTRIC COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0499717-A1 | Ethylenically unsaturated cyclic ortho esters | GENERAL ELECTRIC COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0496116-A1 | Polymers of ethylenically unsaturated cyclic ortho esters | GENERAL ELECTRIC COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5132361-A | Reacting with polymers capable of nucleophilic substitution | GENERAL ELECTRIC COMPANY (US) | 1992-07-21 | — | — | US | disclosed |