SCHEMBL6114371

SCHEMBL6114371

CCN([SiH3])c1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.41
ACHE P22303 1/20 0.41
NPSR1 Q6W5P4 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
ALDH1A1 P00352 3/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
TP53 P04637 1/20 0.37
KDM4E B2RXH2 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
ESR1 P03372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520654 0.78 CYP3A4 (0.46) LMNACYP3A4TSHRACHENPSR1
SCHEMBL328909 0.78 CYP3A4 (0.46) LMNACYP3A4TSHRACHENPSR1
SCHEMBL3682981 0.78 LMNA (0.46) LMNACYP3A4TSHRACHENPSR1
SCHEMBL16612270 0.77 TSHR (0.47) LMNACYP3A4TSHRACHETRPM8
SCHEMBL30800114 0.77 TSHR (0.47) LMNACYP3A4TSHRACHETRPM8
SCHEMBL5430919 0.76 LMNA (0.49) LMNACYP3A4TSHRACHENPSR1
Lithium Ion SCHEMBL19732706 0.76 CYP3A4 (0.44) LMNACYP3A4TSHRACHENPSR1
SCHEMBL21065758 0.76 CYP3A4 (0.44) LMNACYP3A4TSHRACHENPSR1
SCHEMBL28273732 0.76 LMNA (0.44) LMNACYP3A4TSHRACHENPSR1
SCHEMBL8280381 0.75 ACHE (0.45) LMNACYP3A4TSHRACHETRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8912353-B2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-12-16 US claimed
EP-2392691-B1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PROD & CHEM (US) 2014-09-03 EP claimed
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-05-24 US claimed
EP-2392691-A1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-07 EP claimed
US-8912353-B2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-12-16 US disclosed
US-8912353-B2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-12-16 US disclosed
EP-2392691-B1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PROD & CHEM (US) 2014-09-03 EP disclosed
EP-2392691-B1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PROD & CHEM (US) 2014-09-03 EP disclosed
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-05-24 US disclosed
EP-2392691-A1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same C1S, C9, C5 LMNA 110/4885CYP3A4 1699/4885TSHR 4015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.