Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949137 | 0.87 | GPR119 (0.49) | KDM4EPKMGPR119 | |
| SCHEMBL28947907 | 0.86 | KDM4E (0.47) | KDM4EPKMGPR119YAP1 | |
| SCHEMBL578839 | 0.84 | FPR2 (0.53) | KDM4EPKMGPR119 | |
| SCHEMBL6115087 | 0.84 | HTR1A (0.49) | HTR1ACYP2D6SLC6A4MGLL | |
| SCHEMBL2544691 | 0.84 | KDM4E (0.47) | KDM4EPKMGPR119STS | |
| SCHEMBL9943153 | 0.83 | HTR1A (0.43) | KDM4EPKMGPR119YAP1HTR1A | |
| SCHEMBL8773651 | 0.83 | HTR1A (0.43) | KDM4EPKMGPR119YAP1HTR1A | |
| SCHEMBL8773592 | 0.83 | SLC6A4 (0.47) | KDM4EPKMGPR119HTR1ACYP2D6 | |
| SCHEMBL12263494 | 0.83 | KDM4E (0.53) | KDM4EPKMGPR119 | |
| SCHEMBL1363304 | 0.82 | KDM4E (0.51) | KDM4EPKMGPR119STSYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8778970-B2 | Benzyl piperidine compound | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2014-07-15 | — | — | US | disclosed |
| EP-2463286-A1 | BENZYL PIPERIDINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| EP-2463286-A1 | BENZYL PIPERIDINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130077-A1 | BENZYL PIPERIDINE COMPOUND | HTR1D, HTR1A, HTR1B | KDM4E 807/4885PKM 1705/4885GPR119 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.