Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6114864 | 0.92 | HTR1A (0.45) | HTR1ASLC6A4CYP2D6MEN1KMT2A | |
| SCHEMBL8773651 | 0.92 | HTR1A (0.43) | HTR1ASLC6A4KDM4EPKMGPR119 | |
| SCHEMBL8773592 | 0.88 | SLC6A4 (0.47) | HTR1ASLC6A4KDM4EPKMGPR119 | |
| SCHEMBL8837960 | 0.87 | SLC6A4 (0.59) | HTR1ASLC6A4KDM4EPKMCYP2D6 | |
| SCHEMBL15871247 | 0.84 | SLC6A4 (0.61) | HTR1ASLC6A4KDM4ECYP2D6 | |
| SCHEMBL6115159 | 0.83 | KDM4E (0.47) | HTR1ASLC6A4KDM4EPKMGPR119 | |
| SCHEMBL11949137 | 0.82 | GPR119 (0.49) | KDM4EPKMGPR119 | |
| SCHEMBL578839 | 0.79 | FPR2 (0.53) | KDM4EPKMGPR119 | |
| SCHEMBL1363304 | 0.77 | KDM4E (0.51) | KDM4EPKMGPR119YAP1 | |
| SCHEMBL5362064 | 0.77 | ALDH1A1 (0.50) | KDM4EPKMGPR119YAP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463286-A1 | BENZYL PIPERIDINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |