Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | S100A4 | P26447 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | APAF1 | O14727 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GALK1 | P51570 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234836 | 1.00 | PTPRC (0.50) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL24991289 | 0.87 | MEN1 (0.48) | PTPRCMEN1KMT2AMAPK1CES1 | |
| SCHEMBL2198881 | 0.79 | PTPRC (0.65) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL2700387 | 0.79 | DNMT1 (0.59) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL25233080 | 0.77 | MEN1 (0.48) | MEN1KMT2AMAPK1NPSR1RXFP1 | |
| SCHEMBL5145444 | 0.75 | PTPRC (0.59) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL17852139 | 0.75 | ALDH1A1 (0.45) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL29440306 | 0.75 | MEN1 (0.60) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL347152 | 0.75 | MEN1 (0.60) | PTPRCMEN1KMT2AHTTMAPK1 | |
| SCHEMBL29634247 | 0.75 | MEN1 (0.60) | PTPRCMEN1KMT2AHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | PTPRC 4129/4885MEN1 2326/4885KMT2A 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.