Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120278 | 0.88 | APLNR (0.36) | APLNRIDO1TDO2 | |
| SCHEMBL6120132 | 0.85 | ADRB2 (0.33) | — | |
| SCHEMBL6119962 | 0.84 | CYP2C19 (0.37) | APLNR | |
| SCHEMBL6119365 | 0.82 | APLNR (0.33) | APLNR | |
| SCHEMBL6119574 | 0.80 | APLNR (0.36) | APLNR | |
| SCHEMBL6118977 | 0.78 | APLNR (0.36) | APLNR | |
| SCHEMBL6119527 | 0.74 | CA2 (0.32) | APLNR | |
| SCHEMBL6120483 | 0.74 | APLNR (0.37) | APLNR | |
| SCHEMBL6120035 | 0.73 | ADRB2 (0.31) | — | |
| SCHEMBL6120126 | 0.73 | CA2 (0.33) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |