Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120035 | 0.88 | ADRB2 (0.31) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL6119903 | 0.85 | APLNR (0.36) | — | |
| SCHEMBL6119962 | 0.84 | CYP2C19 (0.37) | — | |
| SCHEMBL6119273 | 0.82 | CA2 (0.30) | — | |
| SCHEMBL6119527 | 0.80 | CA2 (0.32) | — | |
| SCHEMBL4773268 | 0.78 | FAAH (0.33) | — | |
| SCHEMBL6120126 | 0.78 | CA2 (0.33) | CYP2D6 | |
| SCHEMBL31303155 | 0.75 | ADRB2 (0.44) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL2500618 | 0.75 | ADRB2 (0.44) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL25976031 | 0.75 | ADRB2 (0.44) | ADRB2ADRB1CYP2D6NFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |