SCHEMBL61205

SCHEMBL61205

CCCCCCCCCCCCCCCCCc1ncc[nH]1.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.46
TERT O14746 1/20 0.39
F2RL1 P55085 3/20 0.35
HTR1A P08908 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
NAMPT P43490 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61763 1.00 TBXAS1 (0.46) TBXAS1TERTF2RL1HTR1ATAAR1
SCHEMBL22163935 1.00 TBXAS1 (0.46) TBXAS1TERTF2RL1HTR1ATAAR1
SCHEMBL22163888 1.00 TBXAS1 (0.46) TBXAS1TERTF2RL1HTR1ATAAR1
SCHEMBL727766 0.95 TBXAS1 (0.42) TBXAS1TERTF2RL1HTR1ATAAR1
SCHEMBL23071637 0.84 TBXAS1 (0.59) TBXAS1TERTHTR1ATAAR1ALDH1A1
SCHEMBL64393 0.84 TBXAS1 (0.59) TBXAS1TERTHTR1ATAAR1ALDH1A1
SCHEMBL73945 0.84 TBXAS1 (0.59) TBXAS1TERTHTR1ATAAR1ALDH1A1
SCHEMBL3497513 0.84 TBXAS1 (0.59) TBXAS1TERTHTR1ATAAR1ALDH1A1
SCHEMBL25380441 0.84 TBXAS1 (0.59) TBXAS1TERTHTR1ATAAR1ALDH1A1
SCHEMBL2775177 0.84 TBXAS1 (0.59) TBXAS1TERTHTR1ATAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4722287-B2 2011-07-13 JP claimed
EP-1056752-B1 Catalyst activators comprising expanded anions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP claimed
US-6395671-B2 ANION CONTAINING TWO LEWIS BASIC SITES WHICH ARE COORDINATED TO LEWIS ACIDS; FOR OLEFIN POLYMERIZATION THE DOW CHEMICAL COMPANY 2002-05-28 US claimed
US-6376406-B1 COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS THE DOW CHEMICAL COMPANY 2002-04-23 US claimed
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US claimed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP claimed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO claimed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3519455-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-10 EP disclosed
EP-4234594-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS Dow Global Technologies LLC (US) 2023-08-30 EP disclosed
EP-2024402-B2 HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-01-25 EP disclosed
US-20220204716-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC 2022-06-30 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
WO-2001058912-A1 DINUCLEAR GROUP 4 METAL BORON OR ALUMINUM BRIDGE CONTAINING ANSA-COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-16 WO disclosed
EP-1119575-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-01 EP disclosed
WO-2001046201-A1 GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-06-28 WO disclosed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed
WO-2000020426-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-04-13 WO disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204716-A1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS ACSL6, ELOVL6, ALOX5 TBXAS1 464/4885TERT 3174/4885F2RL1 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.