Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121001 | 0.92 | SMN1; SMN2 (0.43) | L3MBTL1ALDH1A1CYP3A4SMN1; SMN2KMT2A | |
| SCHEMBL9911862 | 0.87 | MEN1 (0.35) | KMT2AMEN1 | |
| SCHEMBL1936885 | 0.86 | CYP19A1 (0.40) | L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL15941946 | 0.84 | CYP19A1 (0.48) | — | |
| SCHEMBL6121075 | 0.83 | CYP2C9 (0.48) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL2466939 | 0.81 | — | — | |
| SCHEMBL1936371 | 0.80 | CYP3A4 (0.33) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6120945 | 0.80 | ACLY (0.39) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL2464839 | 0.78 | CYP3A4 (0.36) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12164724 | 0.77 | KEAP1 (0.38) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |