Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120949 | 0.92 | L3MBTL1 (0.43) | SMN1; SMN2L3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL2432818 | 0.85 | KEAP1 (0.41) | — | |
| SCHEMBL6120699 | 0.83 | CYP3A4 (0.40) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL15941908 | 0.82 | CYP19A1 (0.47) | — | |
| SCHEMBL12329898 | 0.80 | FPR2 (0.37) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL2467500 | 0.79 | DHODH (0.38) | KMT2AALDH1A1MEN1KDM4EPOLB | |
| SCHEMBL12164724 | 0.78 | KEAP1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL9911862 | 0.78 | MEN1 (0.35) | KMT2AMEN1 | |
| SCHEMBL6120998 | 0.78 | ACLY (0.43) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL2469793 | 0.77 | LMNA (0.40) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |