Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519193 | 0.85 | SMN1; SMN2 (0.54) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL1226530 | 0.85 | SMN1; SMN2 (0.54) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL17797029 | 0.85 | MAPT (0.52) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL9400389 | 0.83 | NPC1 (0.66) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL1549839 | 0.83 | NPC1 (0.63) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL29473469 | 0.83 | NPC1 (0.63) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL22534097 | 0.81 | HSD17B10 (0.56) | NPC1TP53KMT2AMEN1RAB9A | |
| SCHEMBL3859948 | 0.81 | GAA (0.61) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL29807803 | 0.81 | GAA (0.61) | NPC1GAALMNAHTTTP53 | |
| SCHEMBL4946074 | 0.80 | NPC1 (0.73) | NPC1GAALMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515895-B1 | ORAL CARE COMPOSITIONS AND METHODS | COLGATE PALMOLIVE CO (US) | 2018-02-14 | — | — | EP | claimed |
| EP-2307357-A1 | L-MENTHYL-N-(2-HYDROXYPHENYL)CARBAMATE | Symrise AG (DE) | 2011-04-13 | — | — | EP | claimed |
| WO-2009144179-A1 | L-MENTHYL-N-(2-HYDROXYPHENYL)CARBAMATE | SYMRISE GMBH & CO. KG (DE) | 2009-12-03 | — | — | WO | claimed |
| US-20020032934-A1 | Composition for oxidation dyeing of keratin fibers, comprising at least one oxidation base chosen from 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine and addition salts thereof; dyeing processes using them | L'OREAL S.A. (FR) | 2002-03-21 | — | — | US | claimed |
| EP-1155680-A1 | Oxidation dyeing compositions for keratinous fibres comprising at least 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine as oxidation base ; dyeing method of use therof | L'OREAL (FR) | 2001-11-21 | — | — | EP | claimed |
| EP-0649402-A1 | PRO-DRUG CAPABLE OF RELEASING AN OXAZOLIDINONE AND, IF NEED BE, AN ACETAMIDOPHENOL | UNIVERSITE PAUL SABATIER (TOULOUSE III) (FR) | 1995-04-26 | — | — | EP | claimed |
| WO-1994001395-A1 | PRO-DRUG CAPABLE OF RELEASING AN OXAZOLIDINONE AND, IF NEED BE, AN ACETAMIDOPHENOL | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 1994-01-20 | — | — | WO | claimed |
| EP-0142670-B1 | A PROCESS FOR THE PREPARATION OF KNOWN HERBICIDALLY ACTIVE PHENYL CARBAMATES | BEROL NOBEL (SUISSE) S.A. (CH) | 1990-05-23 | — | — | EP | claimed |
| WO-1988009783-A1 | POLYMERIC ULTRAVIOLET LIGHT ABSORBERS | BIOPOLYMERS LIMITED (AU) | 1988-12-15 | — | — | WO | claimed |
| US-4748265-A | Process for the preparation of herbicidally active phenyl carbamates | KEMISK VAERK KOGE A/S (DK) | 1988-05-31 | — | — | US | claimed |
| EP-0142670-A2 | A process for the preparation of known herbicidally active phenyl carbamates | BEROL NOBEL (SUISSE) S.A. (CH) | 1985-05-29 | — | — | EP | claimed |
| WO-1985001286-A1 | A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME | KEMISK VA^ERK KO^/GE A/S (DK) | 1985-03-28 | — | — | WO | claimed |
| CN-118515676-A | Synthetic method and application of cabazitaxel analogue | 湖北省食品质量安全监督检验研究院 | 2024-08-20 | — | — | CN | disclosed |
| WO-2024063670-A1 | CYCLIN-DEPENDENT KINASE 7 INHIBITORS | Акционерное общество "БИОКАД" | 2024-03-28 | — | — | WO | disclosed |
| EP-4314005-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-02-07 | — | — | EP | disclosed |
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2024-01-18 | — | — | US | disclosed |
| WO-1985001286-A1 | A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME | KEMISK VA^ERK KO^/GE A/S (DK) | 1985-03-28 | — | — | WO | disclosed |
| WO-1985001286-A1 | A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME | KEMISK VA^ERK KO^/GE A/S (DK) | 1985-03-28 | — | — | WO | disclosed |
| EP-0097564-A1 | Process for the hydroxylation of phenol and aniline derivatives by hydrogen peroxide in a superacidic medium | ELF ATOCHEM S.A. (FR) | 1984-01-04 | — | — | EP | disclosed |
| US-3997325-A | (Alkynyloxy)alkyl and (alkenyloxy)alkyl carbamates and their use as herbicides | AMERICAN CYANAMID COMPANY (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, NR3C2, MC2R | NPC1 1808/4885GAA 4871/4885LMNA 4758/4885 |
| US-20020032934-A1 | Composition for oxidation dyeing of keratin fibers, comprising at least one oxidation base chosen from 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine and addition salts thereof; dyeing processes using them | KRT18, UNG, DPYD | NPC1 4829/4885GAA 4737/4885LMNA 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.