SCHEMBL612240

SCHEMBL612240

CO[Si](C)(CCCN1CCOCC1)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
KEAP1 Q14145 1/20 0.48
HPGD P15428 1/20 0.44
DUSP3 P51452 1/20 0.44
ALDH1A1 P00352 6/20 0.44
MAPK1 P28482 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
CYP1A2 P05177 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
HTR2A P28223 1/20 0.44
SCN1A P35498 1/20 0.44
HTR2B P41595 1/20 0.44
KCNH2 Q12809 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
TSHR P16473 2/20 0.43
CYP2D6 P10635 1/20 0.43
LMNA P02545 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31687711 0.93 SMN1; SMN2 (0.46) SMN1; SMN2KEAP1HPGDDUSP3ALDH1A1
SCHEMBL31687721 0.91 SMN1; SMN2 (0.44) SMN1; SMN2KEAP1HPGDDUSP3ALDH1A1
SCHEMBL31687716 0.91 SMN1; SMN2 (0.44) SMN1; SMN2KEAP1HPGDDUSP3ALDH1A1
SCHEMBL11897269 0.88 CSNK2A2 (0.38) SMN1; SMN2HPGDALDH1A1SIGMAR1KCNH2
SCHEMBL125043 0.85 SMN1; SMN2 (0.48) SMN1; SMN2KEAP1HPGDDUSP3ALDH1A1
SCHEMBL3482540 0.85 SMN1; SMN2 (0.48) SMN1; SMN2KEAP1HPGDDUSP3ALDH1A1
SCHEMBL8083018 0.84 CSNK2A2 (0.43) HPGDALDH1A1SIGMAR1HRH3USP2
SCHEMBL1995694 0.84 HRH3 (0.44) SMN1; SMN2ALDH1A1MAPK1CYP1A2KCNH2
SCHEMBL4941372 0.83 KEAP1 (0.47) SMN1; SMN2KEAP1HPGDDUSP3ALDH1A1
SCHEMBL611596 0.82 HRH3 (0.48) SMN1; SMN2ALDH1A1MAPK1CYP1A2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183396-A1 METHODS OF MANUFACTURING CONJUGATED DIENE POLYMERS AND THE POLYMERS, RUBBERS AND TIRES MADE THEREFROM TSRC CORPORATION (TW) 2023-06-15 US claimed
EP-4194226-A1 METHODS OF MANUFACTURING CONJUGATED DIENE-BASED POLYMERS AND THE POLYMERS, RUBBERS AND TIRES MADE THEREFROM TSRC Corporation (TW) 2023-06-14 EP claimed
CN-116253835-A Method for producing conjugated diene polymer, and conjugated diene polymer, rubber and tire obtained thereby 台橡股份有限公司 2023-06-13 CN claimed
US-20150056383-A1 High Resolution Printing INTRINSIQ MATERIALS LTD. (GB) 2015-02-26 US claimed
EP-2742783-A1 HIGH RESOLUTION PRINTING Intrinsiq Materials Limited UK (GB) 2014-06-18 EP claimed
WO-2013024280-A1 HIGH RESOLUTION PRINTING INTRINSIQ MATERIALS LTD (GB) 2013-02-21 WO claimed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP claimed
US-5236465-A Method for shrink-proof treatment of fabric of keratinous fibers with organopolysiloxane compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-17 US claimed
US-5232611-A Polysiloxane blend SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-03 US claimed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US claimed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP claimed
EP-3950724-B1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZEON CORP (JP) 2026-02-18 EP disclosed
US-12139572-B2 Conjugated diene copolymer and method for manufacturing conjugated diene copolymer ZS ELASTOMERS CO., LTD. (JP) 2024-11-12 US disclosed
EP-3604365-B1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL CO (JP) 2024-04-24 EP disclosed
CN-113748134-B Conjugated diene copolymer and method for producing conjugated diene copolymer 瑞住合成橡胶株式会社 2024-03-08 CN disclosed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP disclosed
US-5236465-A Method for shrink-proof treatment of fabric of keratinous fibers with organopolysiloxane compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-17 US disclosed
US-5232611-A Polysiloxane blend SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-03 US disclosed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US disclosed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP disclosed