Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 9/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL1239805 | 1.00 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL11440379 | 0.97 | CA1 (0.52) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL613527 | 0.96 | CA1 (0.58) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL160025 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL11046980 | 0.93 | CA1 (0.63) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL3936260 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL3975767 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL125143 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL105755 | 0.93 | CA1 (0.63) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL6562957 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725006-B2 | Hydrophilic berberine-type derivative and application thereof in preparing drug | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-08-15 | — | — | US | claimed |
| CN-110372688-B | 8-dihalomethylene dihydroberberine type compound and anti-infection and anti-inflammatory application thereof | 中国医学科学院药物研究所 | 2021-08-13 | — | — | CN | claimed |
| EP-4221503-B1 | FUNGICIDAL COMPOSITIONS COMPRISING TRIALKYL SULFONIUM SALTS | HELM AG (DE) | 2025-08-20 | — | — | EP | disclosed |
| US-20240208900-A1 | SYNTHESIS OF DIMETHYL-C17-32-ALKYL SULFONIUM SALTS | HELM AG (DE) | 2024-06-27 | — | — | US | disclosed |
| EP-4323337-A1 | SYNTHESIS OF DIMETHYL-C17-32-ALKYL SULFONIUM SALTS | Helm AG (DE) | 2024-02-21 | — | — | EP | disclosed |
| US-20240032533-A1 | TRIALKYL SULFONIUM SALTS | HELM AG (DE) | 2024-02-01 | — | — | US | disclosed |
| CN-117242054-A | dimethyl-C 17-32 Synthesis of alkyl sulfonium salts | 汉姆股份公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-115340538-B | 8-phenyliminomethyl berberine derivative and application thereof in preparation of medicines | 中国医学科学院药物研究所 | 2023-10-20 | — | — | CN | disclosed |
| US-11725006-B2 | Hydrophilic berberine-type derivative and application thereof in preparing drug | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-08-15 | — | — | US | disclosed |
| EP-4221503-A1 | TRIALKYL SULFONIUM SALTS | Helm AG (DE) | 2023-08-09 | — | — | EP | disclosed |
| WO-2022218721-A1 | SYNTHESIS OF DIMETHYL-C17-32-ALKYL SULFONIUM SALTS | HELM AG (DE) | 2022-10-20 | — | — | WO | disclosed |
| EP-2559424-A1 | Cooling composition comprising trimethyl isopropyl butanamide | Kraft Foods Global Brands LLC (US) | 2013-02-20 | — | — | EP | disclosed |
| WO-2012024469-A1 | MOUTH-MOISTENING GUM COMPOSITIONS AND PRODUCTS CONTAINING THE SAME | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20120040057-A1 | CONFECTIONERIES PROVIDING MOUTH-MOISTENING REFRESHMENT | INTERCONTINENTAL GREAT BRANDS LLC | 2012-02-16 | — | — | US | disclosed |
| EP-1493336-B1 | Monomenthyl ester derivatives of dicarboxylic acids, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INT FLAVORS & FRAGRANCES INC (US) | 2009-02-25 | — | — | EP | disclosed |
| US-20070221236-A1 | Cooling compositions including menthyl esters | CADBURY ADAMS USA LLC. | 2007-09-27 | — | — | US | disclosed |
| US-20070077331-A1 | Cooling compositions | CADBURY ADAMS USA LLC. | 2007-04-05 | — | — | US | disclosed |
| US-6884906-B2 | Menthyl half acid ester derivatives, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-20050004214-A1 | MENTHYL HALF ACID ESTER DIRIVATIVES, PROCESSES FOR PREPARING SAME, AND USES THEREOF FOR THEIR COOLING/REFRESHING EFFECT IN CONSUMABLE MATERIALS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2005-01-06 | — | — | US | disclosed |
| EP-1493336-A2 | Monomenthyl ester derivatives of dicarboxylic acids, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240032533-A1 | TRIALKYL SULFONIUM SALTS | STS, STK39, TST | CA1 2201/4885FABP3 2864/4885FFAR3 2727/4885 |
| US-20240208900-A1 | SYNTHESIS OF DIMETHYL-C17-32-ALKYL SULFONIUM SALTS | STS, MRPS34, MRPS22 | CA1 1242/4885FABP3 4041/4885FFAR3 1040/4885 |
| US-20050004214-A1 | MENTHYL HALF ACID ESTER DIRIVATIVES, PROCESSES FOR PREPARING SAME, AND USES THEREOF FOR THEIR COOLING/REFRESHING EFFECT IN CONSUMABLE MATERIALS | TAS2R41, TAS2R1, TAS1R3 | CA1 1405/4885FABP3 4148/4885FFAR3 166/4885 |
| US-11725006-B2 | Hydrophilic berberine-type derivative and application thereof in preparing drug | SLC7A1, ABCB11, ABCC1 | CA1 2869/4885FABP3 3050/4885FFAR3 1665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.