Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FASN | P49327 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125216 | 1.00 | ALOX5 (0.54) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL5967546 | 1.00 | ALOX5 (0.54) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL6128445 | 0.89 | ALOX5 (0.54) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL26468535 | 0.86 | ALOX5 (0.48) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL14642715 | 0.85 | ALOX5 (0.44) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL15198933 | 0.84 | ALOX5 (0.78) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL26468543 | 0.83 | ALOX5 (0.38) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL26468541 | 0.78 | FASN (0.41) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL22702965 | 0.78 | ALOX5 (0.43) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL26468550 | 0.75 | DHODH (0.34) | ALOX5KDM4EMEN1AKR1B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138884-A1 | HUMULUS SPECIES AS INDUSTRIAL CHEMICAL FEEDSTOCKS | P2 SCIENCE, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230138884-A1 | HUMULUS SPECIES AS INDUSTRIAL CHEMICAL FEEDSTOCKS | P2 SCIENCE, INC. | 2023-05-04 | — | — | US | disclosed |
| US-8829056-B2 | Cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl) cyclopent-2-en-1-one derivatives, substantially enantiomerically pure compositions and methods | KINDEX PHARMACEUTICALS, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-8829056-B2 | Cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl) cyclopent-2-en-1-one derivatives, substantially enantiomerically pure compositions and methods | KINDEX PHARMACEUTICALS, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130217781-A1 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | KINDEX THERAPEUTICS, LLC (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130217781-A1 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | KINDEX THERAPEUTICS, LLC (US) | 2013-08-22 | — | — | US | disclosed |
| US-8410178-B2 | CIS 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-derivatives, substantially enantiomerically pure compositions and methods | KINDEX THERAPEUTICS, LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410179-B2 | Cis, 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-derivatives, substantially enantiomerically pure compositions and methods | KINDEX THERAPEUTICS, LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-20130018105-A1 | CIS, 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | KINDEX PHARMACEUTICALS, INC. | 2013-01-17 | — | — | US | disclosed |
| US-20120108671-A1 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | KINDEX PHARMACEUTICALS, INC. | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217781-A1 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | GPR119, FFAR3, FFAR1 | ALOX5 501/4885KDM4E 2365/4885MEN1 4507/4885 |
| US-20130018105-A1 | CIS, 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | GPR119, FFAR3, FFAR1 | ALOX5 525/4885KDM4E 2244/4885MEN1 4443/4885 |
| US-20230138884-A1 | HUMULUS SPECIES AS INDUSTRIAL CHEMICAL FEEDSTOCKS | LSS, HSD17B14, HARS1 | ALOX5 664/4885KDM4E 3627/4885MEN1 4704/4885 |
| US-20120108671-A1 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS | GPR119, FFAR3, FFAR1 | ALOX5 501/4885KDM4E 2365/4885MEN1 4507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.