SCHEMBL612561

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10235665	0.87	LPL (0.41)	REN
	SCHEMBL610600	0.87	TAAR1 (0.37)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL611314	0.82	TAAR1 (0.38)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL611295	0.82	KIF11 (0.39)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL14979521	0.82	HTR6 (0.35)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL609751	0.82	TAAR1 (0.42)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL13959420	0.81	TAAR1 (0.44)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL610502	0.81	TAAR1 (0.39)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL611290	0.79	TAAR1 (0.43)	TAAR1DRD2DRD1MAOANOS1
	SCHEMBL14642761	0.78	TAAR1 (0.44)	TAAR1DRD2DRD1MAOANOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.