Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001252 | 0.79 | NOTUM (0.60) | NOTUMKCNN4KCNA3TDP1KDM4E | |
| SCHEMBL27833547 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL6366299 | 0.74 | NOTUM (0.58) | NOTUMKCNN4KCNA3TDP1KDM4E | |
| SCHEMBL30776885 | 0.74 | NOTUM (0.58) | NOTUMKCNN4KCNA3TDP1KDM4E | |
| SCHEMBL31208430 | 0.70 | SETD7 (0.34) | NOTUMALDH1A1MAPTLMNACYP2D6 | |
| SCHEMBL7960787 | 0.69 | NOTUM (0.53) | NOTUMKCNN4KCNA3TDP1KDM4E | |
| SCHEMBL28855145 | 0.69 | NOTUM (0.58) | NOTUMKCNN4KCNA3KDM4EALDH1A1 | |
| SCHEMBL6360254 | 0.69 | NOTUM (0.53) | NOTUMSMN1; SMN2KCNN4KCNA3KDM4E | |
| SCHEMBL14516311 | 0.69 | NOTUM (0.53) | NOTUMKCNN4KCNA3KDM4EALDH1A1 | |
| SCHEMBL1048074 | 0.69 | NOTUM (1.00) | NOTUMKCNN4KCNA3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432428-A1 | Agent for colouring fibres containing keratin | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-2640698-A1 | NAMPT AND ROCK INHIBITORS | AbbVie Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012067965-A1 | NAMPT AND ROCK INHIBITORS | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | WO | disclosed |