Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982165 | 0.84 | KIF11 (0.47) | NOTUMHTR2CPRKCZCA12CA2 | |
| SCHEMBL1982310 | 0.84 | CYP3A4 (0.41) | NOTUMHTR2CPRKCZCA12CA2 | |
| SCHEMBL1983109 | 0.84 | CYP3A4 (0.41) | NOTUMHTR2CPRKCZCA12CA2 | |
| SCHEMBL6123402 | 0.84 | CYP3A4 (0.41) | NOTUMHTR2CPRKCZCA12CA2 | |
| SCHEMBL1983143 | 0.84 | KIF11 (0.47) | NOTUMHTR2CPRKCZCA12CA2 | |
| SCHEMBL1988497 | 0.84 | CYP3A4 (0.41) | NOTUMHTR2CPRKCZCA12CA2 | |
| SCHEMBL2374410 | 0.84 | RIPK1 (0.38) | PRKCZCYP3A4ACHEHRH3 | |
| SCHEMBL1989822 | 0.84 | RIPK1 (0.38) | PRKCZCYP3A4ACHEHRH3 | |
| SCHEMBL1985242 | 0.74 | LPL (0.38) | NOTUMHTR2CPRKCZCA2CA9 | |
| SCHEMBL1985257 | 0.74 | LPL (0.38) | NOTUMHTR2CPRKCZCA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455376-A1 | Heterocyclic compounds as inhibitors of hepatitis C virus (HCV) | Abbott Laboratories (US) | 2012-05-23 | — | — | EP | disclosed |