Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723346 | 0.80 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14730342 | 0.80 | MAPT (0.38) | MEN1KMT2A | |
| SCHEMBL14723590 | 0.72 | GPR119 (0.40) | GPR119 | |
| SCHEMBL14722740 | 0.70 | GPR119 (0.40) | GPR119 | |
| SCHEMBL461225 | 0.70 | DRD2 (0.34) | MEN1KMT2A | |
| SCHEMBL17115034 | 0.66 | GRIA1 (0.43) | — | |
| SCHEMBL14723457 | 0.64 | KDM1A (0.39) | GPR119 | |
| SCHEMBL31210452 | 0.64 | GPR119 (0.37) | GPR119 | |
| SCHEMBL31082796 | 0.63 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14723557 | 0.63 | GPR119 (0.39) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066077-A1 | 1,4 DI SUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |