Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | USP1 | O94782 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553633 | 0.86 | PPARA (0.50) | PPARAPPARGPPARDALDH1A1GMNN | |
| SCHEMBL6552237 | 0.83 | STS (0.53) | GMNNUSP2LMNATP53CYP1A2 | |
| SCHEMBL6446861 | 0.80 | EPHX2 (0.48) | PPARAPPARGPPARDALDH1A1GMNN | |
| SCHEMBL2414598 | 0.79 | HPGD (0.38) | ALDH1A1LMNATP53POLBRAB9A | |
| SCHEMBL6552622 | 0.76 | PPARA (0.80) | PPARAPPARGPPARDALDH1A1GMNN | |
| SCHEMBL6553638 | 0.74 | PPARA (0.40) | PPARAPPARGPPARDALDH1A1GMNN | |
| SCHEMBL12436841 | 0.73 | PPARA (0.63) | PPARAPPARGPPARDALDH1A1GMNN | |
| SCHEMBL6129078 | 0.73 | CA1 (0.49) | ALDH1A1USP2LMNACYP3A4ALOX15 | |
| SCHEMBL23417577 | 0.72 | MEN1 (0.67) | ALDH1A1LMNAPOLBMAPTMEN1 | |
| SCHEMBL19334502 | 0.71 | NPC1 (0.56) | ALDH1A1LMNATP53POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101542-A1 | Combination therapy for controlling appetites | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-05-12 | — | — | US | disclosed |
| US-20050054730-A1 | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-03-10 | — | — | US | disclosed |
| WO-2005002524-A2 | COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES OF OLEOYLETHANOLAMIDE-LIKE COMPOUNDS AND MODULATORS OF PPARα | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-13 | — | — | WO | disclosed |
| EP-1149063-B1 | UREIDO-THIOBUTYRIC ACID DERIVATIVES AS PPAR-AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2004034968-A2 | COMBINATION THERAPY FOR CONTROLLING APPETITES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-04-29 | — | — | WO | disclosed |
| EP-1149063-A2 | UREIDO-THIOBUTYRIC ACID DERIVATIVES AS PPAR-AGONISTS | GLAXO GROUP LIMITED (GB) | 2001-10-31 | — | — | EP | disclosed |
| US-6306854-B1 | ARYLTHIOALKYLACIDS AND ALKYL UREAS | GLAXOSMITHKLINE | 2001-10-23 | — | — | US | disclosed |
| WO-2000023407-A2 | UREIDO-THIOBUTYRIC ACID DERIVATIVES AS PPAR-AGONISTS | GLAXO GROUP LIMITED (GB) | 2000-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101542-A1 | Combination therapy for controlling appetites | FAAH, FAAH2, GPR119 | PPARA 7/4885PPARG 16/4885PPARD 26/4885 |
| US-20050054730-A1 | Compounds, compositions and treatment of oleoylethanolamide-like modulators of PPARalpha | PPARA, CNR2, CNR1 | PPARA 1/4885PPARG 11/4885PPARD 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.