Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129053 | 0.80 | PPARA (0.47) | EPHX2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL6129078 | 0.78 | CA1 (0.49) | EPHX2RAB9AMEN1KMT2ALMNA | |
| SCHEMBL19334502 | 0.77 | NPC1 (0.56) | EPHX2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23417577 | 0.75 | MEN1 (0.67) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL26998182 | 0.74 | TRPV1 (0.44) | EPHX2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL15678782 | 0.71 | EPHX2 (0.52) | EPHX2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10499905 | 0.71 | MEN1 (0.67) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL13401881 | 0.71 | ATM (0.63) | MEN1KMT2AALDH1A1HSD17B10POLB | |
| SCHEMBL25411196 | 0.70 | MMP2 (0.46) | EPHX2RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL25411190 | 0.70 | MMP2 (0.46) | EPHX2RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101542-A1 | Combination therapy for controlling appetites | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101542-A1 | Combination therapy for controlling appetites | FAAH, FAAH2, GPR119 | EPHX2 330/4885RAB9A 1949/4885MEN1 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.