Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.71 |
| ▸ | TUBB | P07437 | 1/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.71 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.68 |
| ▸ | TERT | O14746 | 4/20 | 0.68 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613755 | 0.89 | TERT (0.77) | CYP1B1CYP1A1TERTAURKAKDR | |
| SCHEMBL16894651 | 0.88 | TUBB4A (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6614365 | 0.88 | TERT (0.80) | CYP1B1CYP1A1TERTAURKAKDR | |
| SCHEMBL8934506 | 0.87 | TUBB4A (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5442940 | 0.87 | TUBB4A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13325112 | 0.86 | TUBB4A (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30082749 | 0.84 | ALDH1A1 (0.79) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL1764091 | 0.84 | ALDH1A1 (0.79) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL8934505 | 0.83 | CYP1A1 (0.69) | CYP1B1CYP1A1TERTAURKAKDR | |
| SCHEMBL4288186 | 0.83 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| US-20050065213-A1 | Combretastatin a-4 derivatives having antineoplastic activity | LAWRENCE NICHOLAS JAMES (GB) | 2005-03-24 | — | — | US | disclosed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065213-A1 | Combretastatin a-4 derivatives having antineoplastic activity | AURKA, AURKB, HDAC4 | TUBB4A 61/4885TUBB 472/4885TUBA3C 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.