Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | HPGD | P15428 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | ELANE | P08246 | 1/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30082749 | 1.00 | ALDH1A1 (0.79) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL1764085 | 0.93 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL30082747 | 0.90 | ALDH1A1 (0.79) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL678646 | 0.90 | ALDH1A1 (0.79) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL30445844 | 0.90 | BCL2 (0.79) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL1764426 | 0.90 | BCL2 (0.79) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| SCHEMBL16894632 | 0.89 | ACHE (0.76) | ALDH1A1CYP3A4MAPTMAPK1CYP1A1 | |
| Nobiletin SCHEMBL22092292 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| Nobiletin SCHEMBL29374681 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPTMAPK1MEN1 | |
| Nobiletin SCHEMBL30049905 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| EP-2010194-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | Rutgers, The State University of New Jersey (US) | 2009-01-07 | — | — | EP | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | disclosed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | disclosed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2011-05-26 | — | — | US | disclosed |
| EP-1883300-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | Rutgers, The State University of New Jersey (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | disclosed |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | WELLGEN, INC. | 2007-04-19 | — | — | US | disclosed |
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-02-22 | — | — | US | disclosed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | GYS1, PYGM, PRDX5 | ALDH1A1 3163/4885CYP3A4 144/4885MAPT 4515/4885 |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | FABP4, PLIN5, PLIN3 | ALDH1A1 1272/4885CYP3A4 1574/4885MAPT 3872/4885 |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | ALDH1A1 1794/4885CYP3A4 390/4885MAPT 4329/4885 |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | GYS1, PYGM, PRDX5 | ALDH1A1 3163/4885CYP3A4 144/4885MAPT 4515/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | ALDH1A1 1794/4885CYP3A4 390/4885MAPT 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.