Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 12/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.38 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845033 | 0.89 | TSPO (0.45) | TSPOPLA2G2AHTR6PLA2G10PLA2G1B | |
| SCHEMBL27515865 | 0.88 | TSPO (0.43) | TSPOPLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL7050807 | 0.87 | HTR6 (0.47) | TSPOPLA2G2AHTR6PLA2G10 | |
| SCHEMBL6129618 | 0.86 | FABP4 (0.37) | TSPOPLA2G2AHTR6 | |
| SCHEMBL6129638 | 0.86 | HTR6 (0.46) | TSPOPLA2G2AHTR6PLA2G10 | |
| SCHEMBL817430 | 0.85 | PLA2G2A (0.58) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2F | |
| SCHEMBL29862343 | 0.85 | PLA2G2A (0.58) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2F | |
| SCHEMBL6129588 | 0.85 | FABP4 (0.36) | TSPOPLA2G2AHTR6 | |
| SCHEMBL6129679 | 0.85 | FABP4 (0.38) | PLA2G2AHTR6PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL5864560 | 0.83 | PLA2G2A (0.57) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043991-A4 | TREATMENT FOR ALZHEIMER'S DISEASE | LILLY CO ELI (US) | 2005-02-02 | — | — | EP | claimed |
| JP-2001522884-A | — | — | 2001-11-20 | — | — | JP | claimed |
| EP-1043991-A1 | TREATMENT FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999025340-A1 | TREATMENT FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | claimed |
| EP-1043991-A4 | TREATMENT FOR ALZHEIMER'S DISEASE | LILLY CO ELI (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1043991-A1 | TREATMENT FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999025340-A1 | TREATMENT FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | disclosed |