SCHEMBL6130089

SCHEMBL6130089

CC(C)CCCSSCCCC(C)C

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
FOLH1 Q04609 1/20 0.34
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
BLM P54132 1/20 0.32
GPR84 Q9NQS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16899661 0.89 LMNA (0.38) LMNAFOLH1
SCHEMBL6130047 0.88 LMNA (0.48) LMNACTSLCTSBBLM
SCHEMBL18226959 0.85
SCHEMBL10941218 0.83 LMNA (0.38) LMNA
SCHEMBL22307383 0.83 HTR1A (0.34) LMNA
SCHEMBL8991455 0.80 LMNA (0.45) LMNACTSLCTSBBLMGPR84
SCHEMBL16710740 0.79 LMNA (0.35) LMNAGPR84
SCHEMBL2124275 0.79 CTSL (0.42) LMNACTSLCTSB
SCHEMBL292457 0.78
SCHEMBL19067184 0.75 OPRM1 (0.50) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
CN-108473484-A Compounds useful as TRPM8 modulators 赛诺米克斯公司 2018-08-31 CN disclosed
EP-1299402-A4 PROCESS FOR THE PREPARATION OF HIGHER-ALKANE SULFONYL HALIDES CHEVRON PHILLIPS CHEMICAL CO (US) 2005-09-28 EP disclosed
EP-1299402-A1 PROCESS FOR THE PREPARATION OF HIGHER-ALKANE SULFONYL HALIDES Philips Petroleum Company (US) 2003-04-09 EP disclosed
US-6441229-B1 REACTING A SULFUR COMPOUND AND HALOGEN COMPOUND IN PRESENCE OF PHASE TRANSFER COMPOUND PHILLIPS PETROLEUM COMPANY 2002-08-27 US disclosed
WO-2002000671-A1 PROCESS FOR THE PREPARATION OF HIGHER-ALKANE SULFONYL HALIDES PHILIPS PETROLEUM COMPANY (US) 2002-01-03 WO disclosed
CN-1033227-C Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and their use. SANKYO CO (JP) 1996-11-06 CN disclosed
CN-1072686-A Has Pyrmidine nucleoside derivatives of anti-tumor activity and its production and use SANKYO CO (JP) 1993-06-02 CN disclosed