SCHEMBL6130102

SCHEMBL6130102

CCC(CC)(C(=O)ON)C(=O)ON

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130103 0.87 MEN1 (0.34) MEN1KMT2A
SCHEMBL25302909 0.87
SCHEMBL27640188 0.87 DGAT1 (0.39)
SCHEMBL28390462 0.83
SCHEMBL27561741 0.82 ALDH1A1 (0.34)
SCHEMBL28841697 0.80 DGAT1 (0.31)
Trifluoroacetic Acid SCHEMBL16569145 0.80 S1PR1 (0.32) MEN1KMT2A
Glycine SCHEMBL16569115 0.80 GLRA1 (0.40) MEN1KMT2A
SCHEMBL2256615 0.78 CYP4F2 (0.38) ALOX15
SCHEMBL7171989 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160220689-A1 MACROMOLECULES OF DENDRIMER-PLATINUM CONJUGATES STARPHARMA PTY LTD. (AU) 2016-08-04 US disclosed
WO-2015035446-A1 MACROMOLECULES OF DENDRIMER-PLATINUM CONJUGATES STARPHARMA PTY LTD (AU) 2015-03-19 WO disclosed
EP-1315735-A4 PHOSPHATE DERIVATIVES AS IMMUNOREGULATORY AGENTS MERCK & CO INC (US) 2005-04-06 EP disclosed
EP-1315735-A1 PHOSPHATE DERIVATIVES AS IMMUNOREGULATORY AGENTS Merck & Co., Inc. (US) 2003-06-04 EP disclosed
US-6437165-B1 USEFUL FOR TREATING IMMUNE MEDIATED DISEASES AND CONDITIONS, SUCH AS BONE MARROW, ORGAN AND TISSUE TRANSPLANT REJECTION. MERCK & CO., INC. 2002-08-20 US disclosed
US-20020091105-A1 Phosphate derivatives as immunoregulatory agents MERCK & CO., INC. 2002-07-11 US disclosed
WO-2002018395-A1 PHOSPHATE DERIVATIVES AS IMMUNOREGULATORY AGENTS MERCK & CO., INC. (US) 2002-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091105-A1 Phosphate derivatives as immunoregulatory agents ALPP, PPIP5K2, ALPI ALOX15 3093/4885MEN1 2130/4885KMT2A 4836/4885
US-20160220689-A1 MACROMOLECULES OF DENDRIMER-PLATINUM CONJUGATES CD44, FOLR1, FOLH1 ALOX15 4633/4885MEN1 1146/4885KMT2A 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.