SCHEMBL6130815

SCHEMBL6130815

N=C(N)NCCCC[C@@](N)(NC(=N)N)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALB P02768 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727982 0.81 ODC1 (0.43) CYP1A2KMT2ASMN1; SMN2
SCHEMBL28827545 0.80 ALOX15 (0.36) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL8709507 0.79 FDPS (0.36) ALOX15MEN1CYP1A2KMT2A
SCHEMBL7718396 0.79 ALOX15 (0.41) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL27855641 0.79 ALOX15 (0.35) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL28434665 0.78 FDPS (0.35) ALOX15MEN1CYP1A2KMT2A
SCHEMBL6130817 0.78 ALOX15 (0.44) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL16447216 0.77 ALOX15 (0.35) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL9112258 0.75 ALOX15 (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL1560751 0.75 MEN1 (0.41) MEN1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1545460-A4 INSULIN MOLECULE HAVING PROTRACTED TIME ACTION LILLY CO ELI (US) 2005-11-16 EP disclosed
EP-1545460-A2 INSULIN MOLECULE HAVING PROTRACTED TIME ACTION ELI LILLY AND COMPANY (US) 2005-06-29 EP disclosed
US-20050014679-A1 Insulin molecule having protracted time action ELI LILLY AND COMPANY 2005-01-20 US disclosed
WO-2003053339-A2 INSULIN MOLECULE HAVING PROTRACTED TIME ACTION ELI LILLY AND COMPANY (US) 2003-07-03 WO disclosed