Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350331 | 0.75 | KDM4E (0.39) | S1PR1S1PR4S1PR3S1PR5LMNA | |
| SCHEMBL6130895 | 0.74 | KDM4E (0.43) | LMNAPPARGKMT2ANPC1RAB9A | |
| SCHEMBL2350428 | 0.73 | LMNA (0.43) | MMP3S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL2355128 | 0.70 | LMNA (0.44) | MMP3S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL23752186 | 0.70 | LMNA (0.44) | MMP3S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6130896 | 0.70 | PPARG (0.41) | PPARG | |
| SCHEMBL2349886 | 0.69 | LMNA (0.37) | MMP3S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL5053052 | 0.68 | TSHR (0.55) | S1PR1S1PR4S1PR3CETP | |
| SCHEMBL2348810 | 0.67 | KDM4E (0.41) | S1PR1S1PR4S1PR3S1PR5CETP | |
| SCHEMBL2353883 | 0.67 | CPN1 (0.50) | S1PR1S1PR4S1PR3CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |