Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352682 | 0.87 | AURKA (0.43) | PPARGBACE1MGLL | |
| SCHEMBL2352657 | 0.71 | PPARG (0.49) | PPARGBACE1MGLL | |
| SCHEMBL2352681 | 0.71 | BACE1 (0.44) | PPARGBACE1MGLL | |
| SCHEMBL6130895 | 0.70 | KDM4E (0.43) | PPARG | |
| SCHEMBL6130871 | 0.70 | MMP3 (0.41) | PPARG | |
| SCHEMBL4710021 | 0.68 | PRTN3 (0.44) | — | |
| SCHEMBL27554195 | 0.67 | PTPN1 (0.49) | — | |
| SCHEMBL2352675 | 0.65 | PPARG (0.49) | PPARGBACE1MGLL | |
| SCHEMBL2933823 | 0.65 | PRTN3 (0.44) | PPARG | |
| SCHEMBL2353853 | 0.64 | ELANE (0.51) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |