Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 4/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131265 | 0.77 | KDR (0.64) | AURKALTA4HAURKBEPHX2KDR | |
| SCHEMBL2697822 | 0.77 | JAK3 (0.63) | AURKARPS6KB1LTA4HAURKBEPHX2 | |
| SCHEMBL22773342 | 0.72 | THRB (0.56) | NPC1RAB9AKDM4EPPARG | |
| SCHEMBL4403211 | 0.72 | STAT6 (0.56) | AURKARPS6KB1AURKB | |
| SCHEMBL11898739 | 0.71 | NPC1 (0.97) | LTA4HNPC1RAB9AKDR | |
| SCHEMBL10132797 | 0.71 | EPHX2 (0.67) | AURKALTA4HNPC1RAB9AAURKB | |
| SCHEMBL12607689 | 0.70 | KDR (0.64) | NPC1RAB9AKDRKDM4E | |
| SCHEMBL1395845 | 0.70 | LTA4H (0.61) | LTA4HNPC1RAB9AEPHX2KDM4E | |
| SCHEMBL4974321 | 0.70 | EPHX2 (0.70) | LTA4HNPC1RAB9AEPHX2KDR | |
| SCHEMBL3007594 | 0.70 | GAA (0.71) | LTA4HNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245518-A1 | Antiproliferative agents | METHYLGENE, INC. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245518-A1 | Antiproliferative agents | HDAC1, HDAC11, HDAC5 | FFAR1 4354/4885AURKA 496/4885RPS6KB1 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.