Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046721 | 0.84 | KIF11 (0.39) | KIF11KCNH2ALDH1A1SLC6A1SLC6A11 | |
| SCHEMBL6046722 | 0.81 | KIF11 (0.41) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL6046726 | 0.77 | KIF11 (0.46) | KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2 | |
| SCHEMBL6131386 | 0.76 | KIF11 (0.43) | KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2 | |
| SCHEMBL2400336 | 0.74 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL2385290 | 0.74 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL6040158 | 0.74 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL13575115 | 0.74 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL4300671 | 0.73 | KIF11 (0.42) | KIF11KCNH2SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL6570209 | 0.71 | CASR (0.44) | KIF11KCNH2SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962784-B2 | Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes | GILEAD SCIENCES, INC. (US) | 2005-11-08 | — | — | US | disclosed |