Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046722 | 0.82 | KIF11 (0.41) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL6046726 | 0.80 | KIF11 (0.46) | KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2 | |
| SCHEMBL6046721 | 0.79 | KIF11 (0.39) | KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2 | |
| SCHEMBL13575115 | 0.78 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL2385290 | 0.78 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL2400336 | 0.78 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL6040158 | 0.78 | SLC6A11 (0.46) | KIF11KCNH2SLC6A1SLC6A11 | |
| SCHEMBL6131385 | 0.76 | KIF11 (0.40) | KIF11KCNH2SLC6A1SLC6A11SMN1; SMN2 | |
| SCHEMBL4421575 | 0.76 | KIF11 (0.45) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL2490410 | 0.72 | SLC6A11 (0.50) | KIF11KCNH2SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962784-B2 | Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes | GILEAD SCIENCES, INC. (US) | 2005-11-08 | — | — | US | disclosed |