SCHEMBL2400336

SCHEMBL2400336

COc1ccc(C(OCCOCCOCCO)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.46
SLC6A1 P30531 2/20 0.46
KIF11 P52732 7/20 0.44
KCNH2 Q12809 1/20 0.42
TK2 O00142 1/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC6A12 P48065 1/20 0.41
SLC6A13 Q9NSD5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13575115 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL6040158 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL2385290 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL6570212 0.92 SLC6A11 (0.47) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL992028 0.91 SLC6A11 (0.50) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2490410 0.91 SLC6A11 (0.50) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL2288433 0.90 SLC6A11 (0.43) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL24207815 0.87 KIF11 (0.55) SLC6A1KIF11TK2MEN1CYP1A2
SCHEMBL3485522 0.87 KIF11 (0.55) SLC6A1KIF11TK2MEN1CYP1A2
SCHEMBL24207971 0.87 KIF11 (0.55) SLC6A1KIF11TK2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF SHIVALILA CHIKDU SHAKTI (US) 2025-10-02 US disclosed
EP-4522744-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2025-03-19 EP disclosed
WO-2023220440-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2023-10-05 US disclosed
CN-109072221-A The design method of variation primer 大研医器株式会社 2018-12-21 CN disclosed
US-8026349-B2 Polynucleotide synthesis labeling chemistry DHARMACON, INC. (US) 2011-09-27 US disclosed
US-20080009612-A1 Novel Polynucleotide Synthesis Labeling Chemistry DHARMACON, INC. 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009612-A1 Novel Polynucleotide Synthesis Labeling Chemistry POLN, POLRMT, POLM SLC6A11 3189/4885SLC6A1 3259/4885KIF11 1922/4885
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND RNGTT, PPA1, PNP SLC6A11 3617/4885SLC6A1 4239/4885KIF11 4046/4885
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF ADAR, NSUN2, RNGTT SLC6A11 4777/4885SLC6A1 4770/4885KIF11 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.